Thermo Fisher Scientific RBBP6 Polyclonal Antibody
RBBP6 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, IP 등에 사용 가능. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 1 mg/mL 농도. 연구용으로만 사용.
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- PA523054
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Immunoprecipitation (IP) | 1:10–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to an internal portion of the human RBBP6 protein (between residues 1600–1650) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152136 |
Product Specific Information
This antibody is predicted to react with mouse based on 100% sequence homology.
Target Information
This gene encodes a cilia-associated protein belonging to the kinesin family. It plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It acts as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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