Thermo Fisher Scientific DECR2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:25–1:100

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total DECR2 protein.

Target Information

DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292-amino-acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily.
Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
DECR2 also shows catalytic activity toward 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate-limiting step in the degradation of docosahexaenoic acid in the peroxisome.
DECR2 is expressed as three isoforms produced by alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.