Thermo Fisher Scientific DECR2 Polyclonal Antibody
인체 DECR2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, IHC(P) 등 다양한 연구 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA551236
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human DECR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636684 |
Product Specific Information
This antibody detects endogenous levels of total DECR2 protein.
Target Information
DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292-amino-acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily.
Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
DECR2 also shows catalytic activity toward 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate-limiting step in the degradation of docosahexaenoic acid in the peroxisome.
DECR2 is expressed as three isoforms produced by alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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