Thermo Fisher Scientific PAX5 Monoclonal Antibody (OTI4F9), TrueMAB
인간 PAX5 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 1 mg/mL 농도의 동결건조 형태이며, 트레할로스를 포함한 PBS 버퍼에 보관합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested Dilution 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): Tested Dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F9 |
| Immunogen | Full length human recombinant protein of human PAX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PAX5 is a transcription factor belonging to the paired box (PAX) family. These proteins regulate early development, and altered expression can lead to neoplastic transformation.
PAX5 acts as the B-cell lineage-specific activator protein (BSAP), expressed in early but not late stages of B-cell differentiation. It is also found in developing CNS and testis, suggesting roles in neural development and spermatogenesis.
Mutations in PAX5 are associated with leukemia, including acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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