Thermo Fisher Scientific IL17RC Polyclonal Antibody
IL17RC 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot에 적합하며, 항원 친화성 크로마토그래피로 정제되었습니다. PBS와 글리세롤 기반 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Interleukin 17 Receptor C (amino acids 257–477) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903725 |
Target Information
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines IL-17A and IL-17F have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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