Thermo Fisher Scientific KCC3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KCC3. Recombinant protein control fragment (Product #RP-95796). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC12A6,uniProtId:Q9UHW9-1,ncbiNodeId:9606,antigenRange:42-127,antigenLength:1150,antigenImageFileName:PA5-56975_SLC12A6_Q9UHW9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56975_SLC12A6_Q9UHW9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642904

Product Specific Information

Immunogen sequence: RVRFSSRESV PETSRSEPMS EMSGATTSLA TVALDPPSDR TSHPQDVIED LSQNSITGEH SQLLDDGHKK ARNAYLNNSN YEEGDE

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.

Target Information

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.