Thermo Fisher Scientific MRP4 Monoclonal Antibody (M4I-80)
MRP4 단백질을 인식하는 Rat 모노클로날 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합합니다. 인간, 마우스, 비인간 영장류 반응성을 가지며, 4°C에서 보관하는 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific MRP4 Monoclonal Antibody (M4I-80)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:20 |
| Immunocytochemistry (ICC/IF) | 1:20–1:50 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M4I-80 |
| Immunogen | MRP4 aa 372–431 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Storage Buffer | Tissue culture supernatant with 0.7% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2241992 |
Product Specific Information
The M4I-80 monoclonal antibody was selected after immunization with a fusion protein containing the E. coli maltose-binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372–431.
MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-80 antibody also reacts with the mouse orthologue of the transporter molecule (Mrp4).
Target Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven distinct subfamilies.
This particular protein is a member of the MRP subfamily, which is involved in multi-drug resistance. Although the specific function has not been fully determined, it may play a role in cellular detoxification as a pump for organic anion substrates.
Alternative splicing results in multiple splice variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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