Thermo Fisher Scientific MRP4 Monoclonal Antibody (M4I-80)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:20

-

Immunocytochemistry (ICC/IF)

1:20-1:50

-

Flow Cytometry (Flow)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate

Published species

Human

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

M4I-80

Immunogen

MRP4 aa 372-431

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Storage buffer

tissue culture supernatant with 0.7% BSA

Contains

0.1% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_2241992

Product Specific Information

The M4I-80 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431. MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-80 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).

Target Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.