
Thermo Fisher Scientific Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker) Monoclonal Antibody (KRT19/799)
인간 KRT19 단백질을 인식하는 단클론 항체로, 췌장 줄기세포 마커로 사용됩니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합합니다. Protein A/G로 정제된 액상 형태이며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT19/799 |
| Immunogen | Recombinant human KRT19 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 19 (KRT19) belongs to a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40–68 kDa and have isoelectric points between 4.9–7.8.
Each cytokeratin subtype (numbered 1–20) is expressed in specific epithelial tissues, reflecting both tissue type and differentiation state. Cytokeratin expression patterns are widely used to distinguish epithelial malignancies.
Cytokeratin antibodies assist in differential tumor diagnosis via immunohistochemistry, and are valuable in cytopathology and flow cytometry. Notably, Cytokeratin 19 is not expressed in hepatocytes, aiding identification of liver metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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