Thermo Fisher Scientific RNF213 Polyclonal Antibody
RNF213 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 사람 RNF213 연구용으로 적합하며 E3 ubiquitin ligase 관련 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RNF213 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RNF213. Recombinant protein control fragment (Product #RP-89516) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646662 |
Product Specific Information
Immunogen sequence:
KDPVCLPCDH VHCLRCLRAW FASEQMICPY CLTALPDEFS PAVSQAHREA IEKHARFRQM CNSFFVDLVS TICFKDNAPP EKEVIESLLS LLFVQKGRLR DAAQRHCEHT KSLSPFNDVV DKTPVIRSVI LKLLLKYS
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 79%
Target Information
RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis and the non-canonical Wnt signaling pathway in vascular development. It mediates ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibition of the non-canonical Wnt signaling pathway and promotion of vessel regression. Also exhibits ATPase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.