Thermo Fisher Scientific Amyloid Precursor Protein VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1209)
인간 APP 단백질을 인식하는 알파카 유래 재조합 단일클론 항체입니다. Western blot, IHC, ELISA 등 다양한 분석에 사용 가능합니다. CHO 세포에서 발현되며 8His-Cys 태그가 포함되어 있습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1209 |
| Immunogen | Recombinant Human APP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Amyloid Precursor Protein (APP), also known as Amyloid beta precursor protein, functions as a cell surface kinesin I membrane receptor mediating the axonal transport of beta-secretase and presenilin 1.
APP is important for neurite growth, neuronal adhesion, and axonogenesis.
It is a 100–140 kDa transmembrane glycoprotein existing in several isoforms due to alternative splicing.
Proteolytic cleavage by beta- and gamma-secretases generates beta amyloid, the primary component of senile plaques — a major histopathologic feature of Alzheimer’s disease.
Abnormal regulation and processing of APP are also implicated in Down’s syndrome, early-onset familial Alzheimer’s disease, and cerebral hemorrhage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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