Thermo Fisher Scientific MRGPRX3 Polyclonal Antibody
MRGPRX3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 면역세포염색에 적합하며, 인간 시료에 반응. 친화 크로마토그래피로 정제된 액상 형태로, 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRGPRX3 (Accession Q96LB0), corresponding to amino acid residues P105–I155 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851675 |
Product Specific Information
Antibody detects endogenous levels of total MRGX3.
Target Information
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. Expressed in a subset of IB4-positive small diameter nociceptive dorsal root neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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