Thermo Fisher Scientific HRG Monoclonal Antibody (C4)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-50 µg/mL

-

Immunocytochemistry (ICC/IF)

5-50 µg/mL

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

C4

Immunogen

Recombinant Eukaryotic Rat HRG protein, Leu19-Lys525 (Accession #Q99PS8) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HRG,uniProtId:Q99PS8-1,ncbiNodeId:10114,antigenRange:19-525,antigenLength:525,antigenImageFileName:MA5-51001_HRG_Q99PS8-1_House_mouse.svg,antigenImageFileNamePDP:MA5-51001_HRG_Q99PS8-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091198

Target Information

HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein`s effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.