Thermo Fisher Scientific TFPI Monoclonal Antibody (2E5)

Applications

• ELISA (ELISA)
  Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MIYTMKKVHA LWASVCLLLN LAPAPLNADS EEDEEHTIIT DTELPPLKLM HSFCAFKADD GPCKAIMKRF FFNIFTRQCE EFIYGGCEGN QNRFESLEEC KKMCTRDNAN RIIKTTLQQE KPDFCFLEED PGICRGYITR YFYNNQTKQC ERFKYGGCLG NMNNFETLEE CKNICEDGPN GFQVDNYGTQ LNAVNNSLTP QSTKVPSLFV TKEGTNDGWK NAAHIYQVFL NAFCIHASMF FLGLDSISCL C

Target Information

Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation.
TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
The coagulation process initiates with the formation of a factor VIIa-TF complex, which activates proteases (factors IX and X) and leads to fibrin clot formation.
TFPI inhibits activated factor X and VIIa-TF proteases in an autoregulatory loop.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.