Thermo Fisher Scientific VPS51 Polyclonal Antibody
VPS51 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. 인간에 반응하며, 농도 0.26 mg/mL의 액상 형태입니다. GARP 및 EARP 복합체 연구에 활용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다.
- 카탈로그번호
- PA521674
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 489–721 of C11orf2 (Uniprot ID: Q9UID3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11156373 |
Product Specific Information
- Recommended positive controls: A431, HeLa, HepG2
- Predicted reactivity: Mouse (99%), Zebrafish (88%), Xenopus laevis (83%), Chicken (80%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
VPS51 acts as a component of the GARP complex, which is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is essential for protein retrieval from endosomes to the TGN, lysosome function, cholesterol trafficking, and autophagy.
It also functions as part of the EARP complex, involved in endocytic recycling and associated with Rab4-positive endosomes, promoting recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
주의 사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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