Thermo Fisher Scientific DUSP11 Polyclonal Antibody
DUSP11 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. 인간 시료에 반응하며 IHC(P) 등 다양한 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. 연구용으로만 사용 가능.
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human DUSP11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636601 |
Product Specific Information
This antibody detects endogenous levels of total DUSP11 protein.
Target Information
DUSP11 (dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities, tissue distributions, subcellular localizations, and inducibility by extracellular stimuli. DUSP11 is localized to the nucleus and binds directly to RNA and splicing factors, suggesting involvement in nuclear mRNA metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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