Thermo Fisher Scientific ARHGDIG Polyclonal Antibody
Human ARHGDIG 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 40% 글리세롤 포함. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARHGDIG. Recombinant protein control fragment (Product #RP-101622). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792202 |
Product Specific Information
Immunogen sequence:
DKEGGPPAVD EVLDEAVPEY RAPGRKSLLE IRQLDPDDRS LAKYKRVLLG PLPPAVDPSL PNV
Target Information
The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization, and secretion. The counter-conversion between the active GTP-bound and inactive GDP-bound forms is regulated by proteins that alter GTPase activity or GDP/GTP exchange rates.
Guanine nucleotide-releasing factors (GRFs) increase GDP dissociation, while GDP-dissociation inhibitors (GDIs) decrease it. The Rho GDI subfamily includes Rho GDIα, Ly-GDI (Rho GDIβ, previously GDI/D4), and Rho GDIγ. These proteins interact with several Ras-like GTP-binding proteins such as Rho A, Rho B, Rac, and Cdc42. Ly-GDI is expressed mainly in hematopoietic cells, particularly B and T lymphocyte cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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