Thermo Fisher Scientific TNFRSF11B Polyclonal Antibody
TNFRSF11B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. Human 및 Rat 반응성 확인됨. 고순도 항원 친화 크로마토그래피 정제 및 안정적 PBS 버퍼 제공.
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- PA519841
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 200–300 of Osteoprotegerin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981525 |
Product Specific Information
- For Western Blot, non-specific bands observed at 105 kDa and 14 kDa.
- Predicted to react with mouse, sheep, cow, and pig based on sequence homology.
Target Information
The TNFRSF11B gene encodes a member of the TNF-receptor superfamily. The protein acts as an osteoblast-secreted decoy receptor that negatively regulates bone resorption by binding to its ligand, osteoprotegerin ligand. Both are key extracellular regulators of osteoclast development.
Studies in mice suggest roles in lymph-node organogenesis and vascular calcification.
Alternatively spliced transcript variants have been reported but their full-length nature remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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