Thermo Fisher Scientific TRAC-1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TRAC-1. Recombinant protein control fragment (Product #RP-98228). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRAC-1,uniProtId:Q96EQ8-1,ncbiNodeId:9606,antigenRange:60-142,antigenLength:232,antigenImageFileName:PA5-59607_TRAC-1_Q96EQ8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59607_TRAC-1_Q96EQ8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648869

Product Specific Information

Immunogen sequence: CIATSLKNNK WTCPYCRAYL PSEGVPATDV AKRMKSEYKN CAECDTLVCL SEMRAHIRTC QKYIDKYGPL QELEETAARC VCP

Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 88%.

Target Information

TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.