Thermo Fisher Scientific Unc18-2 Polyclonal Antibody
Unc18-2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 사용 가능. Human 및 Mouse 시료에 반응하며, 정제된 액상 형태로 제공. PBS/glycerol buffer에 보관되며 -20°C에서 안정적 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–280 of human STXBP2 (NP_001120868.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805026 |
Product Specific Information
Immunogen sequence:
MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED INKRREPIPS LEAIYLLSPT EKALIKDFQG TPTFTYKAAH IFFTDTCPEP LFSELGRSRL AKVVKTLKEI HLAFLPYEAQ VFSLDAPHST YNLYCPFRAE ERTRQLEVLA QQIATLCATL QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK ADTPSLGEGP EKTRSQLLIM DRAADPVSPL LHELTFQAMA YDLLDIEQDT YRYETTGLSE AREKAVLLDE
Positive Samples: THP-1, Jurkat, Mouse testis, Mouse thymus
Target Information
This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE complex assembly, and release of cytotoxic granules by natural killer cells.
Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis.
Alternatively spliced transcript variants encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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