Thermo Fisher Scientific SLC51A Polyclonal Antibody
Rabbit polyclonal antibody against human SLC51A. Recognizes recombinant SLC51A protein. Suitable for research use in bile acid transport and steroid metabolism studies. Supplied as liquid form, 0.05 mg/mL concentration. Store at 4°C short term or -20°C...
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Thermo Fisher Scientific SLC51A Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC51A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647534 |
Product Specific Information
- Immunogen sequence: GKEAVLRTLR DTPMMVHTGP CCCCCPCCPR LLLTRKKLQL
- Antigen sequence identity: Mouse - 88%, Rat - 90%
Target Information
SLC51A is an essential component of the Ost-alpha/Ost-beta complex, a heterodimer acting as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. It efficiently transports major bile acid species such as taurocholate. Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (by similarity).
Additionally, SLC51A can transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, playing a role in the enterohepatic circulation of sterols. It can also transport eicosanoids such as prostaglandin E2 (by similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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