Thermo Fisher Scientific MT1 Polyclonal Antibody
C. elegans MT1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody입니다. Western blot 및 ELISA에 사용 가능하며, 고순도 Protein A/G 정제 및 액상 형태로 제공됩니다. 금속 이온 결합 및 산화 스트레스 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | C. elegans |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Caenorhabditis elegans MT1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.5 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3092388 |
Target Information
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues coordinate metal ions using mercaptide linkages. These proteins act as antioxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a protein coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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