Thermo Fisher Scientific BMI-1 Polyclonal Antibody
BMI-1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 및 IHC(P)에서 검증됨. 고순도 정제 및 안정한 액상 형태로 제공. 인체 시료에 반응하며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.03–0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NHQSSFANRPRKS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933816 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Component of the Polycomb group (PcG) multiprotein PRC1 complex, which maintains transcriptional repression of many genes, including Hox genes, during development. The PRC1 complex acts through chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A (Lys-119), resulting in heritable changes in gene expressibility. Within the PRC1 complex, BMI-1 is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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