Thermo Fisher Scientific HSD11B1 Polyclonal Antibody
HSD11B1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, SPR에 사용 가능하며 인간과 랫트 반응성 확인됨. 합성 펩타이드 면역원 기반으로 제작되어 높은 특이성과 재현성을 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Surface Plasmon Resonance (SPR) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HSD11B1 (aa 72–121) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609050 |
Product Specific Information
Peptide sequence:
QKVVSHCLEL GAASAHYIAG TMEDMTFAEQ FVAQAGKLMG GLDMLILNHI
Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 100%
Horse: 93%
Human: 100%
Mouse: 100%
Rabbit: 93%
Rat: 100%
Sheep: 93%
Target Information
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. It can also catalyze the reverse reaction, converting cortisone to cortisol. Excess cortisol is linked to central obesity, and variations in this gene are associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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