Thermo Fisher Scientific CD28 Polyclonal Antibody
Thermo Fisher Scientific의 CD28 Polyclonal Antibody는 Mouse 시료에 반응하는 Goat 유래 항체로, Western blot에 적합합니다. CD28 단백질의 세포 표면 발현 연구에 활용되며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5142686
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD28 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence KEKHLCHTQSSPK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933332 |
Product Specific Information
- The immunizing peptide represents a part of the extracellular domain.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein.
It is a cell adhesion molecule of the immunoglobulin superfamily, constitutively expressed on most peripheral blood T lymphocytes.
CD28 acts as a critical T cell co-stimulatory receptor by binding CD80 and CD86 on antigen-presenting cells, providing an essential second activation signal.
It prevents T cells from entering an anergic or apoptotic state.
In murine lymphoid organs and blood, all CD4+ and CD8+ T cells express CD28.
Expression is highest on immature thymocytes (CD3-, CD8+, CD4+8+, and CD4-8- cells).
Diseases associated with CD28 dysfunction include mycosis fungoides and Sezary’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.