Thermo Fisher Scientific DLC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DLC1. Recombinant protein control fragment (Product #RP-90818). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DLC1,uniProtId:Q96QB1-2,ncbiNodeId:9606,antigenRange:8-133,antigenLength:1528,antigenImageFileName:PA5-53635_DLC1_Q96QB1-2_Rabbit.svg,antigenImageFileNamePDP:PA5-53635_DLC1_Q96QB1-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640619

Product Specific Information

Immunogen sequence: RSWEEHVTHW MGQPFNSDDR NTACHHGLVA DSLQASMEKD ATLNVDRKEK CVSLPDCCHG SELRDFPGRP MGHLSKDVDE NDSHEGEDQF LSLEASTETL VHVSDEDNNA DLCLTDDKQV LNTQGQ

Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 22%.

Target Information

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.