Thermo Fisher Scientific DLC1 Polyclonal Antibody
Human DLC1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% glycerol buffer에 보관됩니다. 종양 억제 관련 연구용으로 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,500–1:5,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DLC1. Recombinant protein control fragment (Product #RP-90818) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640619 |
Product Specific Information
Immunogen sequence:
RSWEEHVTHW MGQPFNSDDR NTACHHGLVA DSLQASMEKD ATLNVDRKEK CVSLPDCCHG SELRDFPGRP MGHLSKDVDE NDSHEGEDQF LSLEASTETL VHVSDEDNNA DLCLTDDKQV LNTQGQ
Highest antigen sequence identity to orthologs:
- Mouse: 68%
- Rat: 22%
Target Information
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins involved in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes related to cytoskeletal changes.
This gene functions as a tumor suppressor in several cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants exist due to alternative promoters and splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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