Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI6B9), TrueMAB
GPR17 단백질을 인식하는 Rat 모노클로날 항체로, 인체 시료에 반응합니다. IHC(P)에서 1:150 희석으로 검증되었으며, 비결합형 액상 형태입니다. PBS/BSA/glycerol 버퍼에 보관하며 -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B9 |
| Immunogen | Synthetic peptide within Human GPR17 N-terminal (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members, representing the largest known class of molecular targets with proven therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase.
It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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