Thermo Fisher Scientific CARM1 Monoclonal Antibody (CARM1/7426)
CARM1 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체입니다. IHC(P) 및 IHC(PFA) 실험에 사용 가능하며, Human 시료에 반응합니다. 단백질 A/G로 정제된 액상 제품으로, 보존제가 포함되지 않아 민감한 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CARM1/7426 |
| Immunogen | Recombinant fragment (around aa200–400) of human CARM1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.
Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation.
Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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