Thermo Fisher Scientific PRKY Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide derived from the internal region of human PRKY

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2556024

Target Information

A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. PRKY (protein kinase, Y-linked) and PRKX (protein kinase, X-linked) are members of the Ser/Thr protein kinase family, both of which belong to the subfamily of cAMP-dependent kinases. Encoded by a gene that is located near the pseudoautosomal region on chromosome Y, PRKY contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Functioning in a similar manner to PRXY, PRKX contains one protein kinase domain and is essential for macrophage differentiation and renal epithelial cell migration. Defects in the genes encoding PRKY and PRXX are associated with sex reversal disorder, namely XX in males and XY in females.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.