Thermo Fisher Scientific Cytokeratin 8 (KRT8) Monoclonal Antibody (K8/383)
인간 Cytokeratin 8 (KRT8)을 인식하는 마우스 단클론 항체로, WB, IHC, ICC, Flow 등 다양한 면역실험에 사용 가능. 고순도 Protein A/G 정제, PBS 기반 액상 형태, 보존제 없음. 세포 구조 및 분화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K8/383 |
| Immunogen | Recombinant human full-length KRT8 protein (Cytokeratin 8, UniProt ID: P05787-1, antigen range: 1–483) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratin 8 is a member of the type II keratin family located on chromosome 12. Type I and II keratins form intermediate filaments in epithelial cells. Cytokeratin 8 typically dimerizes with keratin 18, contributing to structural integrity, signal transduction, and cellular differentiation. Mutations in this gene are associated with cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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