Thermo Fisher Scientific HNRNPQ/SYNCRIP Polyclonal Antibody
HNRNPQ/SYNCRIP 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 인간 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Usage |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20–40 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 1 and 50 of human Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted reactivity by homology: Rat, Mouse.
Target Information
Heterogeneous nuclear ribonucleoprotein (hnRNP) family protein involved in mRNA processing mechanisms. It is a component of the CRD-mediated complex that promotes MYC mRNA stability. Isoforms 1, 2, and 3 associate with pre-mRNA, splicing intermediates, and mature mRNA complexes. Isoform 1 binds to apoB mRNA AU-rich sequences and participates in the APOB mRNA editosome complex, potentially modulating post-transcriptional C-to-U RNA editing via interaction with A1CF, APOBEC1, or RNA. It may be involved in translationally coupled mRNA turnover and cytoplasmic mRNA decay processes. Isoform 3 is associated with vesicle-based mRNA transport through interaction with synaptotagmins. Additionally, it is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex, which mediates transcript-selective translation inhibition during inflammatory responses.
Additional Information
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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