Thermo Fisher Scientific CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (rC5/6462)
인간 CD5 단백질을 인식하는 Mouse monoclonal 항체로, Mantle Cell Lymphoma 마커로 사용됩니다. 파라핀 및 PFA 고정 조직의 IHC에 적합하며, 고순도 Protein A/G 정제 제품입니다. 4°C 보관, 연구용 전용.
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rC5/6462 |
| Immunogen | Recombinant fragment (around aa450–495) of human CD5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. It also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes, with main reactivity in T cell areas of lymph nodes. CD5 is expressed by many T cell leukemias, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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