Thermo Fisher Scientific Kinesin 5B Polyclonal Antibody
Thermo Fisher Scientific의 Kinesin 5B Polyclonal Antibody는 인간 KIF5B 단백질 N-말단 펩타이드(aa 7–56)에 특이적으로 반응하는 토끼 IgG 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human KIF5B (aa 7–56) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884100 |
Product Specific Information
Immunogen sequence:
CNIKVMCRFR PLNESEVNRG DKYIAKFQGE DTVVIASKPY AFDRVFQSST
For short-term use, store at 2–8°C up to 1 week.
For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology:
Cow: 100%
Dog: 100%
Human: 100%
Mouse: 93%
Pig: 100%
Rat: 93%
Zebrafish: 86%
Target Information
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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