Thermo Fisher Scientific KCNMB4 Polyclonal Antibody
KCNMB4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P)에서 사용 가능. 사람과 마우스 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액에 보관하며 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the N-terminal of human potassium large conductance calcium-activated channel, subfamily M, beta member 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2636144 |
Product Specific Information
This antibody detects endogenous levels of total KCNMB4 protein.
Target Information
MaxiK channels are large conductance, voltage- and calcium-sensitive potassium channels that are fundamental to the control of smooth muscle tone and neuronal excitability. These channels are composed of a pore-forming alpha subunit and a modulatory beta subunit. The protein encoded by the KCNMB4 gene acts as an auxiliary beta subunit, slowing activation kinetics, increasing calcium sensitivity, and shifting the voltage range of current activation to more negative potentials compared to the beta 1 subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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