Thermo Fisher Scientific TAS2R50 Polyclonal Antibody
TAS2R50 단백질을 표적하는 Rabbit Polyclonal Antibody로, Western Blot과 Immunohistochemistry에 사용 가능. 합성 펩타이드(aa 150-200)를 항원으로 제작되었으며, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 150–200 of human TAS2R50 conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_962259 |
Product Specific Information
- Reconstitute with 100 µL of distilled water.
- Centrifuge to remove any insoluble material.
Target Information
TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.
This receptor may play a role in the perception of bitterness and is gustducin-linked. It may also contribute to sensing the chemical composition of the gastrointestinal content.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation, and lead to the gating of TRPM5.
TAS2R50 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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