Thermo Fisher Scientific Ebola Virus GP1 (mucin domain deleted) (subtype Sudan, strain Gulu) Recombinant Rabbit Monoclonal Antibody (301)

Applications

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for EBOV-G/Glycoprotein.

Target Information

Ebola virus is an enveloped, negative-stranded RNA virus belonging to the family Filoviridae. It has a distinctive morphology similar to that of Marburg virus but lacks antigenic similarity. Its genome is a nonsegmented RNA strand.

SDS-PAGE profiles demonstrate seven structural proteins:

• NP (104 K)
• GP (125 K)
• L protein (180 K)
• VP40 (40 K)
• ViPX (35 K)
• VP30 (30 K)
• VP24 (24 K)

GP is the major surface spike protein and the only glycosylated viral protein.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.