Thermo Fisher Scientific BEX1/BEX2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human BEX2(Accession Q9BXY8), corresponding to amino acid residues M1-R50. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BEX1/BEX2,uniProtId:Q9HBH7-1,ncbiNodeId:9606,antigenRange:1,antigenLength:125,antigenImageFileName:PA5-100404_BEX1BEX2_Q9HBH7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100404_BEX1BEX2_Q9HBH7-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:BEX1/BEX2,uniProtId:Q9BXY8-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:128,antigenImageFileName:PA5-100404_BEX1BEX2_Q9BXY8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100404_BEX1BEX2_Q9BXY8-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2849916

Product Specific Information

Antibody detects endogenous levels of total BEX1/2.

Target Information

BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.