Thermo Fisher Scientific BMP10 Polyclonal Antibody
BMP10 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도 친화 크로마토그래피 정제 제품입니다. 심장 발달 관련 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22–316 of human BMP10 (NP_055297.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854860 |
Product Specific Information
Immunogen sequence:
SPIMNLEQSP LEEDMSLFGD VFSEQDGVDF NTLLQSMKDE FLKTLNLSDI PTQDSAKVDP PEYMLELYNK FATDRTSMPS ANIIRSFKNE DLFSQPVSFN GLRKYPLLFN VSIPHHEEVI MAELRLYTLV QRDRMIYDGV DRKITIFEVL ESKGDNEGER NMLVLVSGEI YGTNSEWETF DVTDAIRRWQ KSGSSTHQLE VHIESKHDEA EDASSGRLEI DTSAQNKHNP LLIVFSDDQS SDKERKEELN EMISHEQLPE LDNLGLDSFS SGPGEEALLQ MRSNIIYDST ARIRR
Target Information
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins.
Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life.
BMP-10 plays a crucial role in the development of the embryonic heart by stimulating and maintaining cardiomyocyte proliferation.
It can signal through receptor complexes containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6.
Interaction with specific receptors induces SMAD-dependent signaling (SMAD1, SMAD5, SMAD8) and SMAD-independent processes.
BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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