Thermo Fisher Scientific SGPL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SGPL1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789901

Product Specific Information

Immunogen sequence: SRDFDIYRLS NLMTAKGWNL NQLQFPPSIH FCITLLHARK RVAIQFLKDI RESVTQIMKN PKAKTTGMGA IYGMAQTTVD RNMVAELSSV FLDSLYSTDT VTQGSQMNGS PK

Target Information

Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.