Thermo Fisher Scientific DBNL Monoclonal Antibody (OTI6C9), TrueMAB
Human DBNL 단백질을 인식하는 마우스 모노클로날 항체로, IHC(P)에서 1:150 희석으로 검증됨. TrueMAB 형식의 고순도 항체로, PBS 버퍼에 동결건조 상태로 제공. 연구용으로 재구성 및 결합 실험에 적합.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C9 |
| Immunogen | Full length human recombinant protein of human DBNL produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The DBNL gene encodes a highly conserved mini-chromosome maintenance protein (MCM) essential for eukaryotic genome replication initiation. MCM proteins form a hexameric complex crucial for pre-replication complex formation and DNA helicase activity. Phosphorylation by CDC2 kinase reduces helicase activity and chromatin binding. The gene is located on chromosome 8 near PRKDC/DNA-PK, involved in DNA double-strand break repair.
Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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