Thermo Fisher Scientific RNF14 Monoclonal Antibody (OTI3A4), TrueMAB
인간 RNF14 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. E.coli에서 생산된 1–220 아미노산 범위의 재조합 단백질을 면역원으로 사용했습니다. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적입니다.
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Applications
- Western Blot (WB): 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–220 of human RNF14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene contains a RING zinc finger motif involved in protein–protein interactions. It interacts with the androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate tissue. A dominant negative mutant has been shown to inhibit AR-mediated prostate cancer cell growth. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin ligase (E3) in ubiquitination of nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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