Thermo Fisher Scientific PLSCR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PLSCR3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLSCR3,uniProtId:Q9NRY6-1,ncbiNodeId:9606,antigenRange:189-255,antigenLength:295,antigenImageFileName:PA5-64376_PLSCR3_Q9NRY6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64376_PLSCR3_Q9NRY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645685

Product Specific Information

Immunogen sequence: PFLPKFSIQD ADRQTVLRVV GPCWTCGCGT DTNFEVKTRD ESRSVGRISK QWGGLVREAL TDADDFG

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 91%.

Target Information

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.