Thermo Fisher Scientific Human PCDH18 Synthetic Peptide
인간 PCDH18 단백질의 N-말단 18개 아미노산 서열로 구성된 합성 펩타이드. 항체 PA5-20704와 함께 블로킹 펩타이드로 사용 가능. 다양한 조직에서 발현되는 PCDH18 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human PCDH18.
PEP-0819 can be used as a blocking peptide with polyclonal antibody PA5-20704.
Target Information
Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.
Protocadherin 18 (PCDH18) was initially identified through screening of human and mouse ESTs using conserved cytoplasmic domain motifs.
Tissue screening revealed broad PCDH18 expression in tissues such as brain, liver, heart, kidney, lung, and trachea.
PCDH18 expression is temporally and spatially regulated in the mouse embryonic brain and interacts with Disabled-1, an intracellular adapter protein involved in neuronal migration and cell positioning during mammalian brain development.
PCDH18 is also expressed in the developing zebrafish neural tube and central nervous system, suggesting a role in brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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