Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI1E5), TrueMAB
인간 FCER2(CD23) 단백질을 표적으로 하는 Mouse IgG2b 단클론 항체. Western blot 및 유세포분석(Flow Cytometry)에 적합. 1 mg/mL 농도의 액상 형태로, PBS/BSA/glycerol 저장용액 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI1E5), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–321 of human FCER2 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts.
It is identical to the low-affinity IgE receptor found on B cells.
Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphomas.
Functionally, CD23 is involved in B cell growth, differentiation, and IgE production.
Its soluble form acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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