Thermo Fisher Scientific TrxR1 Polyclonal Antibody
Human TrxR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol 포함)에 보존됩니다. 산화 스트레스 연구 및 셀레늄 대사 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TrxR1. Recombinant protein control fragment (Product #RP-104781) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2856602 |
Product Specific Information
Immunogen sequence:
GFDQDMANKI GEHMEEHGIK FIRQFVPIKV EQIEAGTPGR LRVVAQSTNS EEIIEGEYNT VML
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is a homodimer that uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The Sec residue is encoded by the UGA codon, which normally signals translation termination. The 3′ UTR of selenocysteine-containing genes includes a SECIS element necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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