Thermo Fisher Scientific P2X1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 187-253. Recombinant protein control fragment (Product #RP-110019). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:P2X1,uniProtId:P51575-1,ncbiNodeId:9606,antigenRange:187-253,antigenLength:399,antigenImageFileName:PA5-144864_P2X1_P51575-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144864_P2X1_P51575-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092197

Product Specific Information

Immunogen sequence: LFIKNSISFP RFKVNRRNLV EEVNAAHMKT CLFHKTLHPL CPVFQLGYVV QESGQNFSTL AEKGGVV

Antigen sequence identity: Mouse 84%; Rat 82%

Target Information

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.