Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI2H2), TrueMAB
SCAMP2 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로 Western blot 및 Immunocytochemistry에 적합. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol buffer에 보존. 세포막 단백질 연구 및 분비 경로 분석용 연구 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H2 |
| Immunogen | Full length human recombinant protein of human SCAMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking.
In fibroblasts, SCAMPs are concentrated in compartments related to receptor recycling and endocytosis.
In neurons, they are associated with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs have four transmembrane regions and a cytoplasmic tail.
Among the five known SCAMPs, SCAMPs 1–3 contain NPF repeats that interact with EH domain proteins involved in vesicle budding.
SCAMPs 4 and 5 lack these repeats. SCAMPs 1–4 are ubiquitously expressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with synapse maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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