
ELK Biotechnology HSP27 (phospho Ser15) rabbit pAb
HSP27 (phospho Ser15) rabbit polyclonal antibody로, 인간 및 원숭이 시료에 반응합니다. WB, IHC, IF, ELISA에 적합하며 스트레스 반응 단백질 연구에 활용됩니다. 세포 내 스트레스 반응 및 단백질 인산화 연구에 유용합니다.
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제품명
HSP27 (phospho Ser15) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HSP27 around the phosphorylation site of Ser15 (AA range: 5–54) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 26 kDa |
| Gene ID (Human) | 3315 |
| Human Swiss-Prot No. | P04792 |
| Species Reactivity | Human; Monkey |
| Cellular Localization | Cytoplasm, Nucleus, Cytoskeleton (spindle). Cytoplasmic in interphase cells; colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. |
Background
The protein encoded by this gene is induced by environmental stress and developmental changes. It is involved in stress resistance and actin organization, and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are associated with Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
[provided by RefSeq, Oct 2008]
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