ELK Biotechnology Histone H3 (phospho Ser10) rabbit pAb
Histone H3 (phospho Ser10) rabbit polyclonal antibody로, 인산화된 Ser10 부위의 H3 단백질을 특이적으로 인식합니다. WB, IHC, ICC, IF, ELISA 등 다양한 응용에 적합하며, 인간, 생쥐, 랫드, 초파리 시료에 반응합니다. 핵 및 염색체 국소화 단백질 연구에 활용됩니다.
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Histone H3 (phospho Ser10) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Histone H3 (phospho Ser10) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3 |
| Applications | WB; IHC; IHC-f; Flow Cyt; ICC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC: 1/100–1/300; ICC/IF: 1/200–1/1000; ELISA: 1/10000; IHC-f, Flow Cyt: 1/500 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Histone H3.1 around the phosphorylation site of Ser10 (AA range: 1–50). |
| Storage | -20°C, 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kDa |
| Gene ID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No. | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat, Drosophila melanogaster |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4).
The chromatin fiber is further compacted through interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone belonging to the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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