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ELK Biotechnology EGFR (phospho Tyr1092) rabbit pAb
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EGFR (phospho Tyr1092) rabbit pAb는 인산화된 EGFR 단백질을 검출하기 위한 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 세포막 및 핵막 등 다양한 세포 위치에서 EGFR 발현 연구에 적합합니다.
- 카탈로그번호
- ES1301-xxxxx (2개 옵션)
- 판매단위
- pk
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ELK Biotechnology ES1301-100UL EGFR (phospho Tyr1092) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1301-50UL EGFR (phospho Tyr1092) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology EGFR (phospho Tyr1092) rabbit pAb
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EGFR (phospho Tyr1092) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Tyr1092 (AA range: 1061–1110) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 175 kD |
| Gene ID (Human) | 1956 |
| Human Swiss-Prot No. | P00533 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome; Endosome membrane; Nucleus. In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER (PubMed:20674546, PubMed:17909029). Endocytosed upon activation by ligand (PubMed:2790960, PubMed:17182860, PubMed:27153536, PubMed:17909029). Colocalized with GPER1 in the nucleus of estrogen agonist-induced cancer-associated fibroblasts (CAF) (PubMed:20551055). Isoform 2: Secreted. |
| Background | The protein encoded by this gene is a transmembrane glycoprotein that belongs to the protein kinase superfamily. It is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, inducing receptor dimerization and tyrosine autophosphorylation, which leads to cell proliferation. Mutations in this gene are associated with lung cancer (RefSeq, Jun 2016). |
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