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ELK Biotechnology c-Src (phospho Tyr529) rabbit pAb
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인산화된 Tyr529 부위를 인식하는 c-Src 단백질 특이적 rabbit polyclonal antibody입니다. Western blot, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫드, 원숭이에 반응합니다. 세포막, 세포골격, 핵 등 다양한 세포 위치에서 Src 단백질 검출에 유용합니다.
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- ES1293-xxxxx (2개 옵션)
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- pk
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ELK Biotechnology ES1293-100UL c-Src (phospho Tyr529) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1293-50UL c-Src (phospho Tyr529) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology c-Src (phospho Tyr529) rabbit pAb
제품명
c-Src (phospho Tyr529) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr529. AA range: 487-536 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 59 kD |
| GeneID (Human) | 6714 |
| Human Swiss-Prot No | P12931 |
| Cellular Localization | Cell membrane; Lipid-anchor; Mitochondrion inner membrane; Nucleus; Cytoplasm, cytoskeleton; Cytoplasm, perinuclear region; Cell junction, focal adhesion. Localizes to focal adhesion sites following integrin engagement (PubMed:22801373). Localization to focal adhesion sites requires myristoylation and the SH3 domain (PubMed:7525268). Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions (PubMed:19307596). |
| Background | This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Species Reactivity | Human; Mouse; Rat; Monkey |
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