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ELK Biotechnology Connexin 43 (phospho Ser368) rabbit pAb
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ELK Biotechnology Connexin 43 (phospho Ser368) rabbit pAb

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Connexin 43 (phospho Ser368) rabbit polyclonal antibody로, 인산화된 Ser368 부위를 인식합니다. WB, IHC, IF, ELISA에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 세포막 및 갭 접합 단백질 연구에 적합합니다.

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pk
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ELK Biotechnology ES1291-100UL Connexin 43 (phospho Ser368) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1291-50UL Connexin 43 (phospho Ser368) rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology Connexin 43 (phospho Ser368) rabbit pAb

Connexin 43 (phospho Ser368) rabbit pAb

제품 정보

항목 내용
Product name Connexin 43 (phospho Ser368) rabbit pAb
Alternative Names GJA1; GJAL; Gap junction alpha-1 protein; Connexin-43; Cx43; Gap junction 43 kDa heart protein
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from human Connexin 43 around the phosphorylation site of Ser367 (AA range: 332-381)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 43 kD
Gene ID (Human) 2697
Human Swiss-Prot No. P17302
Cellular Localization Cell membrane; Multi-pass membrane protein; Cell junction, gap junction; Endoplasmic reticulum. Localizes at the intercalated disk (ICD) in cardiomyocytes, and the proper localization at ICD is dependent on TMEM65.
Species Reactivity Human; Mouse; Rat

Background

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia, and heart malformations.
[Provided by RefSeq, May 2014]

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